Insulin Suppresses the Expression of Amyloid Precursor Protein, Presenilins, and Glycogen Synthase Kinase-3β in Peripheral Blood Mononuclear Cells

OBJECTIVE: Our objective was to determine whether peripheral blood mononuclear cells express amyloid precursor protein (APP) and other mediators involved in the pathogenesis of Alzheimer's disease and whether their expression is suppressed by insulin. RESEARCH DESIGN AND METHODS: Ten obese type...

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Bibliografiske detaljer
Main Authors: Dandona, Paresh, Mohamed, Islam, Ghanim, Husam, Sia, Chang Ling, Dhindsa, Sandeep, Dandona, Sonny, Makdissi, Antoine, Chaudhuri, Ajay
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2011
Fag:
Endocrine Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100748/
https://ncbi.nlm.nih.gov/pubmed/21411544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-2961
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