Insulin Suppresses the Expression of Amyloid Precursor Protein, Presenilins, and Glycogen Synthase Kinase-3β in Peripheral Blood Mononuclear Cells

OBJECTIVE: Our objective was to determine whether peripheral blood mononuclear cells express amyloid precursor protein (APP) and other mediators involved in the pathogenesis of Alzheimer's disease and whether their expression is suppressed by insulin. RESEARCH DESIGN AND METHODS: Ten obese type...

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Autors principals: Dandona, Paresh, Mohamed, Islam, Ghanim, Husam, Sia, Chang Ling, Dhindsa, Sandeep, Dandona, Sonny, Makdissi, Antoine, Chaudhuri, Ajay
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2011
Matèries:
Endocrine Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100748/
https://ncbi.nlm.nih.gov/pubmed/21411544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-2961
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