Insulin Suppresses the Expression of Amyloid Precursor Protein, Presenilins, and Glycogen Synthase Kinase-3β in Peripheral Blood Mononuclear Cells

OBJECTIVE: Our objective was to determine whether peripheral blood mononuclear cells express amyloid precursor protein (APP) and other mediators involved in the pathogenesis of Alzheimer's disease and whether their expression is suppressed by insulin. RESEARCH DESIGN AND METHODS: Ten obese type...

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Hlavní autoři: Dandona, Paresh, Mohamed, Islam, Ghanim, Husam, Sia, Chang Ling, Dhindsa, Sandeep, Dandona, Sonny, Makdissi, Antoine, Chaudhuri, Ajay
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Endocrine Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100748/
https://ncbi.nlm.nih.gov/pubmed/21411544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2010-2961
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