Context-dependent function of “GATA switch” sites in vivo

Master transcriptional regulators of development often function through dispersed cis elements at endogenous target genes. While cis-elements are routinely studied in transfection and transgenic reporter assays, it is challenging to ascertain how they function in vivo. To address this problem in the...

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Autori principali: Snow, Jonathan W., Trowbridge, Jennifer J., Johnson, Kirby D., Fujiwara, Tohru, Emambokus, Nikla E., Grass, Jeffrey A., Orkin, Stuart H., Bresnick, Emery H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2011
Soggetti:
Hematopoiesis and Stem Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100688/
https://ncbi.nlm.nih.gov/pubmed/21398579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-10-313031
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