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A Single cis Element Maintains Repression of the Key Developmental Regulator Gata2

In development, lineage-restricted transcription factors simultaneously promote differentiation while repressing alternative fates. Molecular dissection of this process has been challenging as transcription factor loci are regulated by many trans-acting factors functioning through dispersed cis elem...

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Detalhes bibliográficos
Main Authors: Snow, Jonathan W., Trowbridge, Jennifer J., Fujiwara, Tohru, Emambokus, Nikla E., Grass, Jeffrey A., Orkin, Stuart H., Bresnick, Emery H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936534/
https://ncbi.nlm.nih.gov/pubmed/20838598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001103
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