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GATA-1-dependent transcriptional repression of GATA-2 via disruption of positive autoregulation and domain-wide chromatin remodeling

Interplay among GATA transcription factors is an important determinant of cell fate during hematopoiesis. Although GATA-2 regulates hematopoietic stem cell function, mechanisms controlling GATA-2 expression are undefined. Of particular interest is the repression of GATA-2, because sustained GATA-2 e...

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Bibliografiske detaljer
Main Authors: Grass, Jeffrey A., Boyer, Meghan E., Pal, Saumen, Wu, Jing, Weiss, Mitchell J., Bresnick, Emery H.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC166395/
https://ncbi.nlm.nih.gov/pubmed/12857954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1432147100
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