Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain

The hematopoietic transcription factor GATA-1 regulates erythropoiesis and β-globin expression. Although consensus GATA-1 binding sites exist throughout the murine β-globin locus, we found that GATA-1 discriminates among these sites in vivo. Conditional expression of GATA-1 in GATA-1-null cells reca...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Johnson, Kirby D., Grass, Jeffrey A., Boyer, Meghan E., Kiekhaefer, Carol M., Blobel, Gerd A., Weiss, Mitchell J., Bresnick, Emery H.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC129342/
https://ncbi.nlm.nih.gov/pubmed/12193659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192285999
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky