Cooperative activities of hematopoietic regulators recruit RNA polymerase II to a tissue-specific chromatin domain

The hematopoietic transcription factor GATA-1 regulates erythropoiesis and β-globin expression. Although consensus GATA-1 binding sites exist throughout the murine β-globin locus, we found that GATA-1 discriminates among these sites in vivo. Conditional expression of GATA-1 in GATA-1-null cells reca...

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Autori principali: Johnson, Kirby D., Grass, Jeffrey A., Boyer, Meghan E., Kiekhaefer, Carol M., Blobel, Gerd A., Weiss, Mitchell J., Bresnick, Emery H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 2002
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC129342/
https://ncbi.nlm.nih.gov/pubmed/12193659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192285999
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