Determinants of the RNase H cleavage specificity of human immunodeficiency virus reverse transcriptase.

We examined the ribonuclease H (RNase H) specificity of human immunodeficiency virus reverse transcriptase (HIV-RT) using heteropolymeric RNAs hybridized to complementary DNAs. Experiments were performed in the presence of excess challenger polymer (poly(rA)-oligo(dT)) to reveal cleavages resulting...

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Hlavní autoři: DeStefano, J J, Mallaber, L M, Fay, P J, Bambara, R A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1993
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC310068/
https://ncbi.nlm.nih.gov/pubmed/7692401
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