Determinants of the RNase H cleavage specificity of human immunodeficiency virus reverse transcriptase.

We examined the ribonuclease H (RNase H) specificity of human immunodeficiency virus reverse transcriptase (HIV-RT) using heteropolymeric RNAs hybridized to complementary DNAs. Experiments were performed in the presence of excess challenger polymer (poly(rA)-oligo(dT)) to reveal cleavages resulting...

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Dades bibliogràfiques

Publicat a:	Nucleic Acids Res
Autors principals:	DeStefano, J J, Mallaber, L M, Fay, P J, Bambara, R A
Format:	Artigo
Idioma:	Inglês
Publicat:	Oxford University Press 1993
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC310068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7692401/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.18.4330
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