Chitosan hydrogel for localized gene silencing

OBJECTIVE: To achieve effective delivery of siRNA into target cells in vivo, we have developed a novel approach of siRNA delivery by using local drug delivery systems. RESULTS: The chitosan hydrogel (CH-HG) displayed a liquid-solid phase transition in a temperature-dependent manner and formed an end...

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Autores principales: Han, Hee Dong, Mora, Edna M, Roh, Ju Won, Nishimura, Masato, Lee, Sun Joo, Stone, Rebecca L, Bar-Eli, Menashe, Lopez-Berestein, Gabriel, Sood, Anil K
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2011
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100632/
https://ncbi.nlm.nih.gov/pubmed/21358280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.9.15185
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