Yüklüyor......
Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab
The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase belonging to the HER family of receptor tyrosine kinases. Receptor activation upon ligand binding leads to down stream activation of the PI3K/AKT, RAS/RAF/MEK/ERK and PLCγ/PKC pathways that influence cell proliferation, surviv...
Kaydedildi:
| Asıl Yazarlar: | , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Landes Bioscience
2011
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100630/ https://ncbi.nlm.nih.gov/pubmed/21293176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.11.9.15050 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|