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The G Protein-Coupled Bile Acid Receptor, TGR5, Stimulates Gallbladder Filling
TGR5 is a G protein-coupled bile acid receptor present in brown adipose tissue and intestine, where its agonism increases energy expenditure and lowers blood glucose. Thus, it is an attractive drug target for treating human metabolic disease. However, TGR5 is also highly expressed in gallbladder, wh...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Endocrine Society
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100601/ https://ncbi.nlm.nih.gov/pubmed/21454404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0460 |
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