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Raf-1 Activation Prevents Caspase 9 Processing Downstream of Apoptosome Formation

In many cell types, growth factor removal induces the release of cytochrome-c from mitochondria that leads to activation of caspase-9 in the apoptosome complex. Here, we show that sustained stimulation of the Raf-1/MAPK1,3 pathway prevents caspase-9 activation induced by serum depletion in CCL39/ΔRa...

詳細記述

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書誌詳細
主要な著者: Cagnol, Sébastien, Mansour, Anna, Van Obberghen-Schilling, Ellen, Chambard, Jean-Claude
フォーマット: Artigo
言語:Inglês
出版事項: Hindawi Publishing Corporation 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100593/
https://ncbi.nlm.nih.gov/pubmed/21637382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/834948
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