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Caspase-9 swings both ways in the apoptosome

For nearly 2 decades, investigators have debated whether cysteinyl-aspartate-specific protease 9 (caspase-9) is activated within the apoptotic protease-activating factor 1 (Apaf-1) apoptosome through proximity-induced homodimerization or through formation of a holoenzyme. Recently, we have demonstra...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Wu, Chu-Chiao, Bratton, Shawn B.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383358/
https://ncbi.nlm.nih.gov/pubmed/28401186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2017.1281865
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