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Photochemical cleavage of leader peptides

We report a photolabile linker compatible with Fmoc solid phase peptide synthesis and Cu(I)-catalyzed alkyne–azide cycloaddition that allows photochemical cleavage to afford a C-terminal peptide fragment with a native amino terminus.

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Detalhes bibliográficos
Main Authors: Bindman, Noah, Merkx, Remco, Koehler, Robert, Herrman, Nicholas, van der Donk, Wilfred A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100556/
https://ncbi.nlm.nih.gov/pubmed/21046030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0cc02945a
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