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Facile Removal of Leader Peptides from Lanthipeptides by Incorporation of a Hydroxy Acid

The biosynthesis of ribosomally synthesized and posttranslationally modified peptide (RiPP) natural products typically involves a precursor peptide that contains a leader peptide that is important for the modification process, and that is removed in the final step by a protease. Genome mining effort...

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Dades bibliogràfiques
Publicat a:J Am Chem Soc
Autors principals: Bindman, Noah A., Bobeica, Silvia C., Liu, Wenshe R., van der Donk, Wilfred A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505723/
https://ncbi.nlm.nih.gov/pubmed/26006047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04681
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