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Efflux transporters- and cytochrome P-450-mediated interactions between drugs of abuse and antiretrovirals
Multidrug regimens and corresponding drug interactions cause many adverse reactions and treatment failures. Drug efflux transporters: P-gp, MRP, BCRP in conjunction with metabolizing enzymes (CYPs) are major factors in such interactions. Most effective combination antiretrovirals (ARV) therapy inclu...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100475/ https://ncbi.nlm.nih.gov/pubmed/20932495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2010.09.012 |
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