Efflux transporters- and cytochrome P-450-mediated interactions between drugs of abuse and antiretrovirals

Multidrug regimens and corresponding drug interactions cause many adverse reactions and treatment failures. Drug efflux transporters: P-gp, MRP, BCRP in conjunction with metabolizing enzymes (CYPs) are major factors in such interactions. Most effective combination antiretrovirals (ARV) therapy inclu...

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Main Authors: Pal, Dhananjay, Kwatra, Deep, Minocha, Mukul, Paturi, Durga K., Budda, Balasubrahmanyam, Mitra, Ashim K.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100475/
https://ncbi.nlm.nih.gov/pubmed/20932495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2010.09.012
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