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Alloreactivity across HLA barriers is mediated by both naïve and antigen-experienced T cells
T-cell responses to allogeneic targets arise predominantly from the naïve pool. However, in man the risk of graft-versus-host disease (GvHD) is increased if the donor has circulating T cells recognizing multiple persistent DNA viruses, suggesting that memory T cells also contribute to the allorespon...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100442/ https://ncbi.nlm.nih.gov/pubmed/21215812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2010.12.711 |
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