Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects

Adoptive transfer of viral antigen-specific memory T cells can reconstitute antiviral immunity, but in a recent report a majority of virus-specific cytotoxic T-lymphocyte (CTL) lines showed in vitro cross-reactivity against allo-human leukocyte antigen (HLA) molecules as measured by interferon-γ sec...

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Detalhes bibliográficos
Main Authors: Melenhorst, J. Joseph, Leen, Ann M., Bollard, Catherine M., Quigley, Máire F., Price, David A., Rooney, Cliona M., Brenner, Malcolm K., Barrett, A. John, Heslop, Helen E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996125/
https://ncbi.nlm.nih.gov/pubmed/20709906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-06-289991
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