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Exploiting cytokine secretion to rapidly produce multivirus-specific T cells for adoptive immunotherapy

Viral infections remain a major cause of morbidity and mortality after hematopoietic stem cell transplantation (HSCT), and conventional small-molecule therapeutics often have modest benefit, high cost and adverse effects. Adoptive transfer of donor-derived virus-specific T cells has been shown to be...

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Detalhes bibliográficos
Main Authors: Fujita, Yuriko, Leen, Ann M, Sun, Jiali, Nakazawa, Yozo, Yvon, Eric, Heslop, Helen E, Brenner, Malcolm K, Rooney, M Cliona
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643068/
https://ncbi.nlm.nih.gov/pubmed/18600178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e318181b4bd
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