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Identification and Characterization of a Transcriptional Silencer Upstream of the Human BRCA2 Gene

Expression of the breast cancer susceptibility tumor-suppressor protein BRCA2, a protein potentially involved in DNA recombination repair, is tightly regulated throughout development. We have identified a transcriptional silencer at the distal end of the human BRCA2 gene promoter. This silencer is i...

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Détails bibliographiques
Auteurs principaux: Sharan, Chakradhari, Hamilton, Nalo M., Parl, Angelika K., Singh, Pramod K., Chaudhuri, Gautam
Format: Artigo
Langue:Inglês
Publié: 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100288/
https://ncbi.nlm.nih.gov/pubmed/10558858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1006/bbrc.1999.1652
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