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A new PCR based method for the generation of nested deletions.

We have developed a simple, PCR-based protocol, random primed/anchored-PCR (RPA-PCR), that allows the selective amplification and efficient cloning of segments that are adjacent to any known sequence. We demonstrate that RPA-PCR can be used to prepare a nested set of evenly spaced deletions suitable...

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Detalhes bibliográficos
Main Authors: Whitcomb, J M, Rashtchian, A, Hughes, S H
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC310022/
https://ncbi.nlm.nih.gov/pubmed/7690475
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