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Role of Bulk Water in Hydrolysis of the Rhodopsin Chromophore

Rhodopsin (Rho) is a prototypical G protein-coupled receptor that changes from an inactive conformational state to a G protein-activating state as a consequence of its retinal chromophore isomerization, 11-cis-retinal → all-trans-retinal. The photoisomerized chromophore covalently linked to Lys(296)...

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Autori principali: Jastrzebska, Beata, Palczewski, Krzysztof, Golczak, Marcin
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099708/
https://ncbi.nlm.nih.gov/pubmed/21460218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.234583
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