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Role of Bulk Water in Hydrolysis of the Rhodopsin Chromophore
Rhodopsin (Rho) is a prototypical G protein-coupled receptor that changes from an inactive conformational state to a G protein-activating state as a consequence of its retinal chromophore isomerization, 11-cis-retinal → all-trans-retinal. The photoisomerized chromophore covalently linked to Lys(296)...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099708/ https://ncbi.nlm.nih.gov/pubmed/21460218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.234583 |
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