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Compensatory Function of Pyk2 Protein in the Promotion of Focal Adhesion Kinase (FAK)-null Mammary Cancer Stem Cell Tumorigenicity and Metastatic Activity

Mammary cancer stem cells (MaCSCs) have been identified as a rare population of cells capable of self-renewal to drive mammary tumorigenesis and metastasis. Nevertheless, relatively little is known about the intracellular signaling pathways regulating self-renewal and metastatic activities of MaCSCs...

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Hlavní autoři: Fan, Huaping, Guan, Jun-Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099673/
https://ncbi.nlm.nih.gov/pubmed/21471206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200717
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