Rap1-GTP-interacting Adaptor Molecule (RIAM) Protein Controls Invasion and Growth of Melanoma Cells

The Mig-10/RIAM/lamellipodin (MRL) family member Rap1-GTP-interacting adaptor molecule (RIAM) interacts with active Rap1, a small GTPase that is frequently activated in tumors such as melanoma and prostate cancer. We show here that RIAM is expressed in metastatic human melanoma cells and that both R...

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Main Authors: Hernández-Varas, Pablo, Coló, Georgina P., Bartolomé, Ruben A., Paterson, Andrew, Medraño-Fernández, Iria, Arellano-Sánchez, Nohemí, Cabañas, Carlos, Sánchez-Mateos, Paloma, Lafuente, Esther M., Boussiotis, Vassiliki A., Strömblad, Staffan, Teixidó, Joaquin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099666/
https://ncbi.nlm.nih.gov/pubmed/21454517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.189811
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