Genome-wide Regulation of 5hmC, 5mC and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells

DNA methylation at the 5-position of cytosine (5mC) in the mammalian genome is a key epigenetic event critical for various cellular processes. The Ten-eleven translocation (Tet) family of 5mC-hydroxylases, which convert 5mC to 5-hydroxymethylcytosine (5hmC), offers a way for dynamic regulation of DN...

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Detalhes bibliográficos
Main Authors: Xu, Yufei, Wu, Feizhen, Tan, Li, Kong, Lingchun, Xiong, Lijun, Deng, Jie, Barbera, Andrew, Zheng, Lijuan, Zhang, Haikuo, Huang, Stephen, Min, Jinrong, Nicholson, Thomas, Chen, Taiping, Xu, Guoliang, Shi, Yang, Zhang, Kun, Shi, Yujiang Geno
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099128/
https://ncbi.nlm.nih.gov/pubmed/21514197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.04.005
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