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Cytosolic H(+) microdomain developed around AE1 during AE1-mediated Cl(−)/HCO(3)(−) exchange

ABSTRACT: Microdomains, regions of discontinuous cytosolic solute concentration enhanced by rapid solute transport and slow diffusion rates, have many cellular roles. pH-regulatory membrane transporters, like the Cl(−)/HCO(3)(−) exchanger AE1, could develop H(+) microdomains since AE1 has a rapid tr...

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Détails bibliographiques
Auteurs principaux: Johnson, Danielle E, Casey, Joseph R
Format: Artigo
Langue:Inglês
Publié: Blackwell Science Inc 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099015/
https://ncbi.nlm.nih.gov/pubmed/21300752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.201483
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