High Throughput Determination of TGFβ1/SMAD3 Targets in A549 Lung Epithelial Cells

BACKGROUND: Transforming growth factor beta 1 (TGFβ1) plays a major role in many lung diseases including lung cancer, pulmonary hypertension, and pulmonary fibrosis. TGFβ1 activates a signal transduction cascade that results in the transcriptional regulation of genes in the nucleus, primarily throug...

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Bibliographic Details
Main Authors: Zhang, Yingze, Handley, Daniel, Kaplan, Tommy, Yu, Haiying, Bais, Abha S., Richards, Thomas, Pandit, Kusum V., Zeng, Qilu, Benos, Panayiotis V., Friedman, Nir, Eickelberg, Oliver, Kaminski, Naftali
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098871/
https://ncbi.nlm.nih.gov/pubmed/21625455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020319
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