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Systematic Exploitation of Multiple Receptor Conformations for Virtual Ligand Screening

The role of virtual ligand screening in modern drug discovery is to mine large chemical collections and to prioritize for experimental testing a comparatively small and diverse set of compounds with expected activity against a target. Several studies have pointed out that the performance of virtual...

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Библиографические подробности
Главные авторы: Bottegoni, Giovanni, Rocchia, Walter, Rueda, Manuel, Abagyan, Ruben, Cavalli, Andrea
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098722/
https://ncbi.nlm.nih.gov/pubmed/21625529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018845
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