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Systematic Exploitation of Multiple Receptor Conformations for Virtual Ligand Screening

The role of virtual ligand screening in modern drug discovery is to mine large chemical collections and to prioritize for experimental testing a comparatively small and diverse set of compounds with expected activity against a target. Several studies have pointed out that the performance of virtual...

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Autors principals: Bottegoni, Giovanni, Rocchia, Walter, Rueda, Manuel, Abagyan, Ruben, Cavalli, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098722/
https://ncbi.nlm.nih.gov/pubmed/21625529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018845
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