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A meningococcal factor H binding protein mutant that eliminates factor H binding enhances protective antibody responses to vaccination
Certain pathogens recruit host complement inhibitors such as factor H (fH) to evade the immune system. Microbial complement inhibitor-binding molecules can be promising vaccine targets by eliciting antibodies that neutralize this microbial defense mechanism. One such antigen, meningococcal fH-bindin...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098282/ https://ncbi.nlm.nih.gov/pubmed/21325619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003470 |
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