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A meningococcal factor H binding protein mutant that eliminates factor H binding enhances protective antibody responses to vaccination
Certain pathogens recruit host complement inhibitors such as factor H (fH) to evade the immune system. Microbial complement inhibitor-binding molecules can be promising vaccine targets by eliciting antibodies that neutralize this microbial defense mechanism. One such antigen, meningococcal fH-bindin...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098282/ https://ncbi.nlm.nih.gov/pubmed/21325619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1003470 |
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