Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors

Pituitary adenylate cyclase activating polypeptide (PACAP) is a member of the PACAP/glucagon family of peptide hormones, which controls many physiological functions in the immune, nervous, endocrine, and muscular systems. It activates adenylate cyclase by binding to its receptor, PAC1R, a member of...

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Bibliografiske detaljer
Main Authors: Kumar, Shiva, Pioszak, Augen, Zhang, Chenghai, Swaminathan, Kunchithapadam, Xu, H. Eric
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098264/
https://ncbi.nlm.nih.gov/pubmed/21625560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019682
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