Protective Efficacy of Serially Up-Ranked Subdominant CD8(+) T Cell Epitopes against Virus Challenges

Immunodominance in T cell responses to complex antigens like viruses is still incompletely understood. Some data indicate that the dominant responses to viruses are not necessarily the most protective, while other data imply that dominant responses are the most important. The issue is of considerabl...

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Main Authors: Im, Eung-Jun, Hong, Jessie P., Roshorm, Yaowaluck, Bridgeman, Anne, Létourneau, Sven, Liljeström, Peter, Potash, Mary Jane, Volsky, David J., McMichael, Andrew J., Hanke, Tomáš
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098219/
https://ncbi.nlm.nih.gov/pubmed/21625575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002041
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