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T cells induced by recombinant chimpanzee adenovirus alone and in prime-boost regimens decrease chimeric EcoHIV/NDK challenge virus load

The popularity of nonreplicating adenoviruses of chimpanzee origin (ChAdVs) as vectors for subunit vaccines is on the rise. This is mainly for their excellent safety and impressive immunogenicity observed in human studies to date. Here, we recloned the chimpanzee adenovirus sero type 68 (ChAdV-68),...

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Detalhes bibliográficos
Main Authors: Roshorm, Yaowaluck, Cottingham, Mathew G., Potash, Mary-Jane, Volsky, David J., Hanke, Tomáš
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980942/
https://ncbi.nlm.nih.gov/pubmed/22930183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242624
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