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Temperature Dependence of the Kinetic Isotope Effects in Thymidylate Synthase. A Theoretical Study
In recent years, the temperature dependence of primary kinetic isotope effects (KIE) has been used as indicator for the physical nature of enzyme catalyzed H-transfer reactions. An interactive study where experimental data and calculations examine the same chemical transformation is a critical means...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098132/ https://ncbi.nlm.nih.gov/pubmed/21476498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja1114369 |
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