ΔNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation

BACKGROUND: ΔNp63α is an epithelial progenitor cell marker that maintains epidermal stem cell self-renewal capacity. Previous studies revealed that UV-damage induced p53 phosphorylation is confined to ΔNp63α-positive cells in the basal layer of human epithelium. RESULTS: We now report that phosphory...

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Detalles Bibliográficos
Autores principales: Craig, Ashley L, Holcakova, Jitka, Finlan, Lee E, Nekulova, Marta, Hrstka, Roman, Gueven, Nuri, DiRenzo, James, Smith, Graeme, Hupp, Ted R, Vojtesek, Borivoj
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098010/
https://ncbi.nlm.nih.gov/pubmed/20663147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-195
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