Anti-apoptotic role of HIF-1 and AP-1 in paclitaxel exposed breast cancer cells under hypoxia

BACKGROUND: Hypoxia is a hallmark of solid tumors and is associated with metastases, therapeutic resistance and poor patient survival. RESULTS: In this study, we showed that hypoxia protected MDA-MB-231 breast cancer cells against paclitaxel- but not epirubicin-induced apoptosis. The possible implic...

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Main Authors: Flamant, Lionel, Notte, Annick, Ninane, Noelle, Raes, Martine, Michiels, Carine
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098009/
https://ncbi.nlm.nih.gov/pubmed/20626868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-191
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