Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity

BACKGROUND: it is now well established that hypoxia renders tumor cells resistant to radio- but also chemotherapy. However, few elements are currently available as for the mechanisms underlying this protection. RESULTS: in this study, physiological hypoxia was shown to inhibit apoptosis induced in H...

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Detalhes bibliográficos
Main Authors: Sermeus, Audrey, Cosse, Jean-Philippe, Crespin, Marianne, Mainfroid, Veronique, de Longueville, Francoise, Ninane, Noelle, Raes, Martine, Remacle, Jose, Michiels, Carine
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2330149/
https://ncbi.nlm.nih.gov/pubmed/18366759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-7-27
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