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Hypoxia-Induced Decrease in p53 Protein Level and Increase in c-jun DNA Binding Activity Results in Cancer Cell Resistance to Etoposide1,

Tumor hypoxia is one of the features of tumor microenvironment that contributes to chemoresistance in particular by cellular adaptations that modulate the apoptotic process. However, the mechanisms involved in this resistance still need deeper understanding. In this study, we investigated the involv...

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Main Authors: Cosse, Jean-Philippe, Ronvaux, Marie, Ninane, Noëlle, Raes, Martine J, Michiels, Carine
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press Inc. 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745664/
https://ncbi.nlm.nih.gov/pubmed/19794957
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