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Anion Binding to Hydrophobic Concavity is Central to the Salting-in Effects of Hofmeister Chaotropes

For over 120 years it has been appreciated that certain salts (kosmotropes) cause the precipitation of proteins, whilst others (chaotropes) increase their solubility. The cause of this, “Hofmeister effect” is still unclear; especially with the original concept that kosmotropic anions “make” water st...

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Bibliographic Details
Main Authors: Gibb, Corinne L. D., Gibb, Bruce C.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098002/
https://ncbi.nlm.nih.gov/pubmed/21524086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja202308n
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