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Binding hydrated anions with hydrophobic pockets

Using a combination of Isothermal Titration Calorimetry and quantum and MD calculations, we demonstrate that relatively soft anions have an affinity for hydrophobic concavity. The results are consistent with the anions remaining partially hydrated upon binding, and suggest a novel strategy for anion...

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Bibliografski detalji
Izdano u:J Am Chem Soc
Glavni autori: Sokkalingam, Punidha, Shraberg, Joshua, Rick, Steven W., Gibb, Bruce C.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5571644/
https://ncbi.nlm.nih.gov/pubmed/26702712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b10937
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