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Anion Binding to Hydrophobic Concavity is Central to the Salting-in Effects of Hofmeister Chaotropes

For over 120 years it has been appreciated that certain salts (kosmotropes) cause the precipitation of proteins, whilst others (chaotropes) increase their solubility. The cause of this, “Hofmeister effect” is still unclear; especially with the original concept that kosmotropic anions “make” water st...

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Detalhes bibliográficos
Main Authors: Gibb, Corinne L. D., Gibb, Bruce C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098002/
https://ncbi.nlm.nih.gov/pubmed/21524086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja202308n
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