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Activation of HIV-specific ribozyme activity by self-cleavage.
A hammerhead ribozyme designed to cleave in trans the R region of HIV-1 RNA was inserted into a eukaryotic expression vector. This ribozyme was studied in vitro using the T3 RNA polymerase promoter located upstream of the eukaryotic promoter. The ribozyme showed no activity against its specific targ...
保存先:
| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
1993
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| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8341599/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.14.3249 |
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