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Activation of HIV-specific ribozyme activity by self-cleavage.

A hammerhead ribozyme designed to cleave in trans the R region of HIV-1 RNA was inserted into a eukaryotic expression vector. This ribozyme was studied in vitro using the T3 RNA polymerase promoter located upstream of the eukaryotic promoter. The ribozyme showed no activity against its specific targ...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Ventura, M, Wang, P, Ragot, T, Perricaudet, M, Saragosti, S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1993
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8341599/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.14.3249
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