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Activation of HIV-specific ribozyme activity by self-cleavage.

A hammerhead ribozyme designed to cleave in trans the R region of HIV-1 RNA was inserted into a eukaryotic expression vector. This ribozyme was studied in vitro using the T3 RNA polymerase promoter located upstream of the eukaryotic promoter. The ribozyme showed no activity against its specific targ...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Ventura, M, Wang, P, Ragot, T, Perricaudet, M, Saragosti, S
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 1993
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309763/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8341599/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.14.3249
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