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The virtues of self-binding: high sequence specificity for RNA cleavage by self-processed hammerhead ribozymes

Naturally occurring hammerhead ribozymes are produced by rolling circle replication followed by self-cleavage. This results in monomer-length catalytic RNAs which have self-complementary sequences that can occupy their trans-binding domains and potentially block their ability to cleave other RNA str...

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Detalhes bibliográficos
Main Authors: Ohmichi, Tatsuo, Kool, Eric T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC102550/
https://ncbi.nlm.nih.gov/pubmed/10637330
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