The virtues of self-binding: high sequence specificity for RNA cleavage by self-processed hammerhead ribozymes
Naturally occurring hammerhead ribozymes are produced by rolling circle replication followed by self-cleavage. This results in monomer-length catalytic RNAs which have self-complementary sequences that can occupy their trans-binding domains and potentially block their ability to cleave other RNA str...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102550/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10637330/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.3.776 |
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