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The virtues of self-binding: high sequence specificity for RNA cleavage by self-processed hammerhead ribozymes

Naturally occurring hammerhead ribozymes are produced by rolling circle replication followed by self-cleavage. This results in monomer-length catalytic RNAs which have self-complementary sequences that can occupy their trans-binding domains and potentially block their ability to cleave other RNA str...

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Publicat a:Nucleic Acids Res
Autors principals: Ohmichi, Tatsuo, Kool, Eric T.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2000
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102550/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10637330/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.3.776
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