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Activation of HIV-specific ribozyme activity by self-cleavage.
A hammerhead ribozyme designed to cleave in trans the R region of HIV-1 RNA was inserted into a eukaryotic expression vector. This ribozyme was studied in vitro using the T3 RNA polymerase promoter located upstream of the eukaryotic promoter. The ribozyme showed no activity against its specific targ...
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| Опубликовано в: : | Nucleic Acids Res |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1993
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| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309763/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8341599/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.14.3249 |
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