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Exploiting Nucleotide Composition to Engineer Promoters

The choice of promoter is a critical step in optimizing the efficiency and stability of recombinant protein production in mammalian cell lines. Artificial promoters that provide stable expression across cell lines and can be designed to the desired strength constitute an alternative to the use of vi...

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Detalles Bibliográficos
Main Authors: Grabherr, Manfred G., Pontiller, Jens, Mauceli, Evan, Ernst, Wolfgang, Baumann, Martina, Biagi, Tara, Swofford, Ross, Russell, Pamela, Zody, Michael C., Di Palma, Federica, Lindblad-Toh, Kerstin, Grabherr, Reingard M.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097237/
https://ncbi.nlm.nih.gov/pubmed/21625601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0020136
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